Domain-oriented functional analysis based on expression profiling

Systematic enrichment analysis of microRNA expression profiling studies in endometriosis

Objective(s): The purpose of this study was to conduct a meta-analysis on human microRNAs (miRNAs) expression data of endometriosis tissue profiles versus those of normal controls and to identify novel putative diagnostic markers. Materials andMethods: PubMed, Embase, Web of Science, Ovid Medline were used to search for endometriosis miRNA expression profiling studies of endometriosis. The miRN...

Gene cloning and expression of soluble thrombopoietin functional domain by harnessing Rosetta-gami expression system

Background: Thrombopoietin (TPO) is an important cytokine that has a critical role in regulating hematopoietic stem cells (HSCs) proliferation and megakaryocyte differentiation. Because of scares amount of this protein in human plasma, in many biotechnological centers around the world, recombinant production of this protein has been carried out. This study was aiming to gene cloning and express...

Pathogenesis analysis of pituitary adenoma based on gene expression profiling

The aim of the current study was to investigate the pathogenesis of pituitary adenoma through screening of the differentially-expressed genes (DEGs) and proteins in normal pituitary and pituitary adenoma tissues, and analyzing the interactions among them. Following the acquisition of gene expression profiling data from a public functional genomics data repository, Gene Expression Omnibus, DEGs ...

Aspect-Oriented Domain Analysis

Context-Oriented Domain Analysis

Context-aware systems are software systems which adapt their behaviour according to the context of use. The requirements engineering phase is recognized as a primordial step to develop robust implementations of context-aware systems since it establishes a comprehensive understanding of the problem space. This paper proposes the Context-Oriented Domain Analysis (CODA) model which is a specialize...